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Association of Anticoagulant Therapy With Risk of Fracture Among Patients With Atrial Fibrillation
Author(s) -
Pamela L. Lutsey,
Faye L. Norby,
Kristine E. Ensrud,
Richard F. MacLehose,
Susan J. Diem,
Lin Y. Chen,
Álvaro Alonso
Publication year - 2019
Publication title -
jama internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.14
H-Index - 342
eISSN - 2168-6114
pISSN - 2168-6106
DOI - 10.1001/jamainternmed.2019.5679
Subject(s) - medicine , atrial fibrillation , warfarin , apixaban , rivaroxaban , dabigatran , propensity score matching , stroke (engine) , hip fracture , population , osteoporosis , mechanical engineering , environmental health , engineering
Warfarin is prescribed to patients with atrial fibrillation (AF) for the prevention of cardioembolic complications. Whether warfarin adversely affects bone health is controversial. The availability of alternate direct oral anticoagulant (DOAC) options now make it possible to evaluate the comparative safety of warfarin in association with fracture risk.

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