Evaluating Progression-Free Survival as a Surrogate Outcome for Health-Related Quality of Life in Oncology | Zendy

Bruno Kovic | Zendy; Xuejing Jin | Zendy; Sean A. Kennedy | Zendy; Mathieu Hylands | Zendy; Michał Pędziwiatr | Zendy; Akira Kuriyama | Zendy; Huda Gomaa | Zendy; Yung Lee | Zendy; Morihiro Katsura | Zendy; Masafumi Tada | Zendy; Brian Y. Hong | Zendy; Sung Min Cho | Zendy; Patrick Jiho Hong | Zendy; Ashley Yu | Zendy; Yasmin Sivji | Zendy; Augustin Toma | Zendy; Li Xie | Zendy; Ludwig Tsoi | Zendy; Marcin Waligóra | Zendy; Manya Prasad | Zendy; Neera Bhatnagar | Zendy; Lehana Thabane | Zendy; Michael Brundage | Zendy; Gordon Guyatt | Zendy; Feng Xie | Zendy

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Evaluating Progression-Free Survival as a Surrogate Outcome for Health-Related Quality of Life in Oncology

Author(s) -

Bruno Kovic,

Xuejing Jin,

Sean A. Kennedy,

Mathieu Hylands,

Michał Pędziwiatr,

Akira Kuriyama,

Huda Gomaa,

Yung Lee,

Morihiro Katsura,

Masafumi Tada,

Brian Y. Hong,

Sung Min Cho,

Patrick Jiho Hong,

Ashley Yu,

Yasmin Sivji,

Augustin Toma,

Li Xie,

Ludwig Tsoi,

Marcin Waligóra,

Manya Prasad,

Neera Bhatnagar,

Lehana Thabane,

Michael Brundage,

Gordon Guyatt,

Feng Xie

Publication year - 2018

Publication title -

jama internal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.14

H-Index - 342

eISSN - 2168-6114

pISSN - 2168-6106

DOI - 10.1001/jamainternmed.2018.4710

Subject(s) - medicine , quality of life (healthcare) , randomized controlled trial , clinical trial , meta analysis , medline , progression free survival , oncology , chemotherapy , nursing , political science , law

Progression-free survival (PFS) has become a commonly used outcome to assess the efficacy of new cancer drugs. However, it is not clear if delay in progression leads to improved quality of life with or without overall survival benefit.

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