Risk of Bleeding and Thrombosis in Patients 70 Years or Older Using Vitamin K Antagonists
Author(s) -
Hilde Kooistra,
Agneta Calf,
Margriet PiersmaWichers,
Hanneke C. KluinNelemans,
Gerbrand J. Izaks,
Nic J.G.M. Veeger,
Karina Meijer
Publication year - 2016
Publication title -
jama internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.14
H-Index - 342
eISSN - 2168-6114
pISSN - 2168-6106
DOI - 10.1001/jamainternmed.2016.3057
Subject(s) - medicine , vitamin k antagonist , thrombosis , hazard ratio , major bleeding , cohort , cohort study , surgery , pediatrics , warfarin , confidence interval , myocardial infarction , atrial fibrillation
Previous studies have shown that, despite the higher risk of bleeding, the elderly still benefit from taking anticoagulants if they have a stringent indication. However, owing to the relatively low number of patients older than 90 years in these studies, it is unknown whether this benefit is also seen with the eldest patients.
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