Association Between Achieved Low-Density Lipoprotein Levels and Major Adverse Cardiac Events in Patients With Stable Ischemic Heart Disease Taking Statin Treatment
Author(s) -
Morton Leibowitz,
Tomas Karpati,
Chandra J. Cohen-Stavi,
Becca Feldman,
Moshe Hoshen,
Haim Bitterman,
Samy Suissa,
Ran D. Balicer
Publication year - 2016
Publication title -
jama internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.14
H-Index - 342
eISSN - 2168-6114
pISSN - 2168-6106
DOI - 10.1001/jamainternmed.2016.2751
Subject(s) - medicine , hazard ratio , myocardial infarction , statin , cardiology , propensity score matching , proportional hazards model , unstable angina , population , adverse effect , cohort , stroke (engine) , confidence interval , mechanical engineering , environmental health , engineering
International guidelines recommend treatment with statins for patients with preexisting ischemic heart disease to prevent additional cardiovascular events but differ regarding target levels of low-density lipoprotein cholesterol (LDL-C). Trial data on this question are inconclusive and observational data are lacking.
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