Open AccessEfficacy, Tolerability, and Dose-Dependent Effects of Opioid Analgesics for Low Back Pain
Author(s) -
Christina Abdel Shaheed,
Christopher G. Maher,
Kylie A. Williams,
Richard O. Day,
Andrew J. McLachlan
Publication year - 2016
Publication title -
jama internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.14
H-Index - 342
eISSN - 2168-6114
pISSN - 2168-6106
DOI - 10.1001/jamainternmed.2016.1251
Subject(s) - medicine , tolerability , placebo , opioid , randomized controlled trial , adverse effect , analgesic , anesthesia , meta analysis , chronic pain , physical therapy , alternative medicine , receptor , pathology
Opioid analgesics are commonly used for low back pain, however, to our knowledge there has been no systematic evaluation of the effect of opioid dose and use of enrichment study design on estimates of treatment effect.
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