Effect of Discontinuation of Antihypertensive Treatment in Elderly People on Cognitive Functioning—the DANTE Study Leiden | Zendy

Justine E. F. Moonen | Zendy; Jessica C. FosterDingley | Zendy; Wouter de Ruijter | Zendy; Jeroen van der Grond | Zendy; Anne Suzanne Bertens | Zendy; Mark A. van Buchem | Zendy; Jacobijn Gussekloo | Zendy; Huub A. M. Middelkoop | Zendy; Marieke J.H. Wermer | Zendy; Rudi G. J. Westendorp | Zendy; Anton J.M. de Craen | Zendy; Roos C. van der Mast | Zendy

Open Access

Effect of Discontinuation of Antihypertensive Treatment in Elderly People on Cognitive Functioning—the DANTE Study Leiden

Author(s) -

Justine E. F. Moonen,

Jessica C. FosterDingley,

Wouter de Ruijter,

Jeroen van der Grond,

Anne Suzanne Bertens,

Mark A. van Buchem,

Jacobijn Gussekloo,

Huub A. M. Middelkoop,

Marieke J.H. Wermer,

Rudi G. J. Westendorp,

Anton J.M. de Craen,

Roos C. van der Mast

Publication year - 2015

Publication title -

jama internal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.14

H-Index - 342

eISSN - 2168-6114

pISSN - 2168-6106

DOI - 10.1001/jamainternmed.2015.4103

Subject(s) - medicine , discontinuation , observational study , dementia , quality of life (healthcare) , blood pressure , cognition , neurocognitive , cognitive decline , physical therapy , pediatrics , psychiatry , disease , nursing

Observational studies indicate that lower blood pressure (BP) increases risk for cognitive decline in elderly individuals. Older persons are at risk for impaired cerebral autoregulation; lowering their BP may compromise cerebral blood flow and cognitive function.

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