Rates of Opioid Dispensing and Overdose After Introduction of Abuse-Deterrent Extended-Release Oxycodone and Withdrawal of Propoxyphene | Zendy

Marc R. Larochelle | Zendy; Fang Zhang | Zendy; Dennis RossDegnan | Zendy; J. Frank Wharam | Zendy

Open Access

Rates of Opioid Dispensing and Overdose After Introduction of Abuse-Deterrent Extended-Release Oxycodone and Withdrawal of Propoxyphene

Author(s) -

Marc R. Larochelle,

Fang Zhang,

Dennis RossDegnan,

J. Frank Wharam

Publication year - 2015

Publication title -

jama internal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.14

H-Index - 342

eISSN - 2168-6114

pISSN - 2168-6106

DOI - 10.1001/jamainternmed.2015.0914

Subject(s) - medicine , oxycodone , propoxyphene , opioid , heroin , opioid overdose , drug overdose , anesthesia , poison control , emergency medicine , analgesic , pharmacology , (+) naloxone , drug , receptor

In the second half of 2010, abuse-deterrent extended-release oxycodone hydrochloride (OxyContin; Purdue Pharma) was introduced and propoxyphene was withdrawn from the US market. The effect of these pharmaceutical market changes on opioid dispensing and overdose rates is unknown.

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