Increasing Varenicline Dose in Smokers Who Do Not Respond to the Standard Dosage | Zendy

Peter Hájek | Zendy; Hayden McRobbie | Zendy; Katherine Smith | Zendy; Anna C. Phillips | Zendy; Danielle Cornwall | Zendy; A. Dhanji | Zendy

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Increasing Varenicline Dose in Smokers Who Do Not Respond to the Standard Dosage

Author(s) -

Peter Hájek,

Hayden McRobbie,

Katherine Smith,

Anna C. Phillips,

Danielle Cornwall,

A. Dhanji

Publication year - 2014

Publication title -

jama internal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.14

H-Index - 342

eISSN - 2168-6114

pISSN - 2168-6106

DOI - 10.1001/jamainternmed.2014.6916

Subject(s) - varenicline , medicine , placebo , nausea , dosing , smoking cessation , adverse effect , anesthesia , randomized controlled trial , abstinence , psychiatry , alternative medicine , pathology

Standard varenicline tartrate dosing was formulated to avoid adverse effects (primarily nausea), but some patients may be underdosed. To our knowledge, no evidence-based guidance exists for physicians considering increasing varenicline dose if there is no response to the standard dosage.

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