Antidepressant Dose, Age, and the Risk of Deliberate Self-harm | Zendy

Matthew Miller | Zendy; Sonja A. Swanson | Zendy; Deborah Azrael | Zendy; Virginia Pate | Zendy; Til Stürmer‎ | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Antidepressant Dose, Age, and the Risk of Deliberate Self-harm

Author(s) -

Matthew Miller,

Sonja A. Swanson,

Deborah Azrael,

Virginia Pate,

Til Stürmer‎

Publication year - 2014

Publication title -

jama internal medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.14

H-Index - 342

eISSN - 2168-6114

pISSN - 2168-6106

DOI - 10.1001/jamainternmed.2014.1053

Subject(s) - medicine , hazard ratio , antidepressant , depression (economics) , poison control , absolute risk reduction , randomized controlled trial , population , number needed to harm , injury prevention , placebo , psychiatry , relative risk , number needed to treat , emergency medicine , confidence interval , alternative medicine , environmental health , pathology , hippocampus , economics , macroeconomics

A comprehensive meta-analysis of randomized trial data suggests that suicidal behavior is twice as likely when children and young adults are randomized to antidepressants compared with when they are randomized to placebo. Drug-related risk was not elevated for adults older than 24 years. To our knowledge, no study to date has examined whether the risk of suicidal behavior is related to antidepressant dose, and if so, whether risk depends on a patient's age.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research