Glucagonlike Peptide 1–Based Therapies and Risk of Hospitalization for Acute Pancreatitis in Type 2 Diabetes Mellitus
Author(s) -
Sonal Singh,
HsienYen Chang,
Thomas M. Richards,
Jonathan P. Weiner,
Jeanne M. Clark,
Jodi B Segal
Publication year - 2013
Publication title -
jama internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.14
H-Index - 342
eISSN - 2168-6114
pISSN - 2168-6106
DOI - 10.1001/jamainternmed.2013.2720
Subject(s) - medicine , sitagliptin , exenatide , acute pancreatitis , pancreatitis , diabetes mellitus , metformin , odds ratio , gastroenterology , type 2 diabetes , insulin , endocrinology
Acute pancreatitis has significant morbidity and mortality. Previous studies have raised the possibility that glucagonlike peptide 1 (GLP-1)-based therapies, including a GLP-1 mimetic (exenatide) and a dipeptidyl peptidase 4 inhibitor (sitagliptin phosphate), may increase the risk of acute pancreatitis.
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