Association of Potent and Very Potent Topical Corticosteroids and the Risk of Osteoporosis and Major Osteoporotic Fractures | Zendy

Alexander Egeberg | Zendy; Peter Schwarz | Zendy; Torben Harsløf | Zendy; Y.M.F. Andersen | Zendy; Anton Pottegård | Zendy; Jesper Hallas | Zendy; Jacob P. Thyssen | Zendy

Open Access

Association of Potent and Very Potent Topical Corticosteroids and the Risk of Osteoporosis and Major Osteoporotic Fractures

Author(s) -

Alexander Egeberg,

Peter Schwarz,

Torben Harsløf,

Y.M.F. Andersen,

Anton Pottegård,

Jesper Hallas,

Jacob P. Thyssen

Publication year - 2021

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2020.4968

Subject(s) - medicine , osteoporosis , mometasone furoate , hazard ratio , proportional hazards model , retrospective cohort study , medical prescription , pediatrics , corticosteroid , pharmacology , confidence interval

Systemic and inhaled corticosteroids negatively affect bone remodeling and cause osteoporosis and bone fracture when given continuously or in high doses. However, risk of osteoporosis and major osteoporotic fracture (MOF) after application of topical corticosteroids (TCSs) is largely unexplored.

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