Association Between Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 and Coronary Artery Disease in Psoriasis | Zendy

Amit K. Dey | Zendy; Ranjitha Gaddipati | Zendy; Youssef Elnabawi | Zendy; Emily L. Ongstad | Zendy; Aditya Goyal | Zendy; Jonathan H. Chung | Zendy; Heather Teague | Zendy; Justin Rodante | Zendy; Aparna Sajja | Zendy; Alexander V. Sorokin | Zendy; Sundus S. Lateef | Zendy; Milena Aksentijevich | Zendy; Harry Choi | Zendy; Aarthi Reddy | Zendy; Nevin Varghese | Zendy; Jacob Groenendyk | Zendy; Agastya D. Belur | Zendy; Leonard Genovese | Zendy; Joshua Rivers | Zendy; Joseph B. Lerman | Zendy; Mohammad Tarek Kabbany | Zendy; Charlotte Harrington | Zendy; Jenis Ortiz | Zendy; Noor Khalil | Zendy; Andrew Keel | Zendy; Yvonne Baumer | Zendy; Marcus Y. Chen | Zendy; David A. Bluemke | Zendy; Aditya A. Joshi | Zendy; Mariana J. Kaplan | Zendy; Alan T. Remaley | Zendy; Martin P. Playford | Zendy; Sotirios K. Karathanasis | Zendy; Joel M. Gelfand | Zendy; Ruchi Gupta | Zendy; Nehal N. Mehta | Zendy

Open Access

Association Between Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 and Coronary Artery Disease in Psoriasis

Author(s) -

Amit K. Dey,

Ranjitha Gaddipati,

Youssef Elnabawi,

Emily L. Ongstad,

Aditya Goyal,

Jonathan H. Chung,

Heather Teague,

Justin Rodante,

Aparna Sajja,

Alexander V. Sorokin,

Sundus S. Lateef,

Milena Aksentijevich,

Harry Choi,

Aarthi Reddy,

Nevin Varghese,

Jacob Groenendyk,

Agastya D. Belur,

Leonard Genovese,

Joshua Rivers,

Joseph B. Lerman,

Mohammad Tarek Kabbany,

Charlotte Harrington,

Jenis Ortiz,

Noor Khalil,

Andrew Keel,

Yvonne Baumer,

Marcus Y. Chen,

David A. Bluemke,

Aditya A. Joshi,

Mariana J. Kaplan,

Alan T. Remaley,

Martin P. Playford,

Sotirios K. Karathanasis,

Joel M. Gelfand,

Ruchi Gupta,

Nehal N. Mehta

Publication year - 2019

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2019.3595

Subject(s) - medicine , psoriasis , interquartile range , coronary artery disease , cardiology , lipoprotein , cohort , gastroenterology , dermatology , cholesterol

Psoriasis, a chronic inflammatory skin disease associated with accelerated noncalcified coronary burden (NCB) by coronary computed tomography angiography (CCTA), accelerates lipoprotein oxidation in the form of oxidized modified lipoproteins. A transmembrane scavenger receptor for these oxidized modified lipoproteins is lectinlike oxidized low-density lipoprotein receptor-1 (LOX-1), which has been reported to be associated with coronary artery disease. It is unknown whether this receptor is associated with coronary artery disease in psoriasis.

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