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Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis
Author(s) -
Melinda Gooderham,
Seth Forman,
Robert Bissonnette,
Jean S. Beebe,
Weidong Zhang,
C Banfield,
Linda Zhu,
Jocelyne Papacharalambous,
Michael S. Vincent,
Elena Peeva
Publication year - 2019
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2019.2855
Subject(s) - medicine , atopic dermatitis , contraindication , placebo , population , randomized controlled trial , clinical trial , janus kinase inhibitor , dermatology , pediatrics , janus kinase , alternative medicine , environmental health , pathology , cytokine
Atopic dermatitis is associated with substantial patient and caregiver burden. Currently available treatments for atopic dermatitis are inadequate or contraindicated for some patients. Abrocitinib (PF-04965842) is an oral Janus kinase 1 selective inhibitor under investigation for the treatment of atopic dermatitis.

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