Efficacy and Safety of Guselkumab in Japanese Patients With Palmoplantar Pustulosis
Author(s) -
Tadashi Terui,
Satomi Kobayashi,
Yukari Okubo,
Masamoto Murakami,
Richuan Zheng,
Hitomi Morishima,
Ryosuke Goto,
Takayuki Kimura
Publication year - 2019
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2019.1394
Subject(s) - medicine , palmoplantar pustulosis , placebo , randomized controlled trial , dermatology life quality index , refractory (planetary science) , gastroenterology , surgery , dermatology , psoriasis , pathology , disease , alternative medicine , physics , astrobiology
Palmoplantar pustulosis (PPP) causes erythematous, scaly plaques with recurrent sterile pustules refractory to treatment and with few randomized clinical trials conducted. Evidence points to involvement of interleukin 23 in the pathogenesis of PPP.
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