Development and Validation of a Risk Prediction Model for In-Hospital Mortality Among Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis—ABCD-10 | Zendy

Megan H. Noe | Zendy; Misha Rosenbach | Zendy; Rebecca A. Hubbard | Zendy; Arash Mostaghimi | Zendy; Adela R. Cardones | Zendy; Jennifer K. Chen | Zendy; Jonathan Cotliar | Zendy; Mark D.P. Davis | Zendy; Arturo R. Domínguez | Zendy; Lindy P. Fox | Zendy; Lauren C. Hughey | Zendy; Benjamin H. Kaffenberger | Zendy; Daniela Kroshinsky | Zendy; Bernice Y. Kwong | Zendy; Daniel D. Miller | Zendy; Amy Musiek | Zendy; Alex G. OrtegaLoayza | Zendy; Victoria R. Sharon | Zendy; Kanade Shinkai | Zendy; Erika M. Summers | Zendy; Karolyn A. Wanat | Zendy; David A. Wetter | Zendy; Scott Worswick | Zendy; David J. Margolis | Zendy; Joel M. Gelfand | Zendy; Robert G. Micheletti | Zendy

Open Access

Development and Validation of a Risk Prediction Model for In-Hospital Mortality Among Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis—ABCD-10

Author(s) -

Megan H. Noe,

Misha Rosenbach,

Rebecca A. Hubbard,

Arash Mostaghimi,

Adela R. Cardones,

Jennifer K. Chen,

Jonathan Cotliar,

Mark D.P. Davis,

Arturo R. Domínguez,

Lindy P. Fox,

Lauren C. Hughey,

Benjamin H. Kaffenberger,

Daniela Kroshinsky,

Bernice Y. Kwong,

Daniel D. Miller,

Amy Musiek,

Alex G. OrtegaLoayza,

Victoria R. Sharon,

Kanade Shinkai,

Erika M. Summers,

Karolyn A. Wanat,

David A. Wetter,

Scott Worswick,

David J. Margolis,

Joel M. Gelfand,

Robert G. Micheletti

Publication year - 2019

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2018.5605

Subject(s) - toxic epidermal necrolysis , medicine , mucocutaneous zone , cohort , medical record , odds ratio , emergency medicine , mortality rate , cohort study , retrospective cohort study , receiver operating characteristic , pediatrics , dermatology , disease

Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a spectrum of severe mucocutaneous drug reaction associated with significant morbidity and mortality. A previously developed SJS/TEN-specific severity-of-illness model (Score of Toxic Epidermal Necrolysis [SCORTEN]) has been reported to overestimate and underestimate SJS/TEN-related in-hospital mortality in various populations.

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