Association of APOA5 and APOC3 Genetic Polymorphisms With Severity of Hypertriglyceridemia in Patients With Cutaneous T-Cell Lymphoma Treated With Bexarotene | Zendy

Irene Cabello | Zendy; Pedro Alía | Zendy; Xavier Pintó | Zendy; Cristina Muniesa | Zendy; Ricardo FernándezdeMisa | Zendy; Yeray Peñate | Zendy; Mercedes Morillo | Zendy; Amparo Perez-Farriols | Zendy; Teresa Estrach | Zendy; R. Izu | Zendy; Fernando Gallardo | Zendy; Concepción Román | Zendy; I. Cervigón | Zendy; Ariadna OrtizBrugués | Zendy; Pablo L. OrtizRomero | Zendy; Octavio Servitje | Zendy

Open Access

Association of APOA5 and APOC3 Genetic Polymorphisms With Severity of Hypertriglyceridemia in Patients With Cutaneous T-Cell Lymphoma Treated With Bexarotene

Author(s) -

Irene Cabello,

Pedro Alía,

Xavier Pintó,

Cristina Muniesa,

Ricardo FernándezdeMisa,

Yeray Peñate,

Mercedes Morillo,

Amparo Perez-Farriols,

Teresa Estrach,

R. Izu,

Fernando Gallardo,

Concepción Román,

I. Cervigón,

Ariadna OrtizBrugués,

Pablo L. OrtizRomero,

Octavio Servitje

Publication year - 2018

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2018.3679

Subject(s) - bexarotene , medicine , hypertriglyceridemia , mycosis fungoides , gastroenterology , odds ratio , triglyceride , cholesterol , lymphoma , genetics , nuclear receptor , biology , transcription factor , gene

Hypertriglyceridemia is the most frequent and limiting adverse effect of bexarotene therapy in cutaneous T-cell lymphoma (CTCL). Despite standard prophylactic measures, there is a wide variability in the severity of this complication, which could be associated with both genetic and environmental factors.

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