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Utility of Laboratory Test Result Monitoring in Patients Taking Oral Terbinafine or Griseofulvin for Dermatophyte Infections
Author(s) -
Deirdre Stolmeier,
Hannah B. Stratman,
Thomas J. McIntee,
Erik J. Stratman
Publication year - 2018
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2018.3578
Subject(s) - griseofulvin , terbinafine , medicine , dermatophyte , itraconazole , neutropenia , dermatology , gastroenterology , chemotherapy , antifungal
Terbinafine hydrochloride and griseofulvin are effective oral treatments for dermatophyte infections but have been associated with hepatic and hematologic abnormalities. The prevalence of alanine aminotransferase elevations, aspartate aminotransferase elevations, anemia, lymphopenia, and neutropenia among adults and children taking terbinafine and griseofulvin is unclear.

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