Economic Analysis of a Noninvasive Molecular Pathologic Assay for Pigmented Skin Lesions | Zendy

John Hornberger | Zendy; Daniel M. Siegel | Zendy

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Economic Analysis of a Noninvasive Molecular Pathologic Assay for Pigmented Skin Lesions

Author(s) -

John Hornberger,

Daniel M. Siegel

Publication year - 2018

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2018.1764

Subject(s) - medicine , biopsy , melanoma , medicaid , lesion , sampling (signal processing) , stage (stratigraphy) , surgery , dermatology , radiology , health care , cancer research , economics , economic growth , paleontology , filter (signal processing) , biology , computer science , computer vision

A recently described noninvasive gene expression test (the pigmented lesion assay [PLA]) with adhesive patch-based sampling has the potential to rule out melanoma and the need for surgical biopsy of pigmented lesions suggestive of melanoma with a negative predictive value of 99% compared with 83% for the histopathologic standard of care. The cost implications of using this molecular test vs visual assessment followed by biopsy and histopathologic assessment (VAH) have not been evaluated.

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