Evaluating Comorbidities, Natural History, and Predictors of Early Resolution in a Cohort of Children With Chronic Urticaria
Author(s) -
Eleetchiporouk,
Denis Sasseville,
Linda Moreau,
Youssef Habel,
Elham Rahme,
Moshe BenShoshan
Publication year - 2017
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2017.3182
Subject(s) - medicine , cohort , comorbidity , autoimmune thyroiditis , pediatrics , retrospective cohort study , cohort study , natural history , immunology , thyroiditis , disease
Chronic urticaria (CU) affects 0.1% to 0.3% of children. Most cases have no identifiable trigger and are classified as chronic spontaneous urticaria (CSU). At least half of patients with CSU may have an autoimmune etiology that can be determined in vitro using the basophil activation test (BAT). While 30% to 55% of CU cases resolve spontaneously within 5 years in adults, the natural history and predictors of resolution in children are not known.
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