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Association of Multiple Primary Skin Cancers With Human Immunodeficiency Virus Infection, CD4 Count, and Viral Load
Author(s) -
Maryam M. Asgari,
G. Thomas Ray,
Charles P. Quesenberry,
Kenneth A. Katz,
Michael J. Silverberg
Publication year - 2017
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2017.1716
Subject(s) - medicine , skin cancer , cohort , viral load , proportional hazards model , hazard ratio , basal cell carcinoma , incidence (geometry) , cohort study , immunology , human immunodeficiency virus (hiv) , cancer , confidence interval , basal cell , physics , optics
Persons with human immunodeficiency virus (HIV) have a 2.8-fold higher risk than HIV-uninfected persons of nonmelanoma skin cancer (NMSC), defined as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Individuals with a prior NMSC history are at increased risk for subsequent NMSC, but the magnitude of risk and its relation to HIV disease-related factors, including CD4 count and viral load (VL), are unknown.

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