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Utility of a Noninvasive 2-Gene Molecular Assay for Cutaneous Melanoma and Effect on the Decision to Biopsy
Author(s) -
Laura K. Ferris,
Burkhard Jansen,
Jonhan Ho,
Klaus J. Busam,
Kenneth G. Gross,
Doyle Hansen,
John P. Alsobrook,
Zuxu Yao,
Gary L. Peck,
Pedram Gerami
Publication year - 2017
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2017.0473
Subject(s) - medicine , biopsy , melanoma , lesion , pathology , dermatology , cancer research
Expression of long intergenic non-protein coding RNA 518 (LINC00518) and preferentially expressed antigen in melanoma (PRAME) genes, obtained via noninvasive adhesive patch biopsy, is a sensitive and specific method for detection of cutaneous melanoma. However, the utility of this test in biopsy decisions made by dermatologists has not been evaluated.

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