Human Determinants and the Role of Melanocortin-1 Receptor Variants in Melanoma Risk Independent of UV Radiation Exposure | Zendy

Judith Wendt | Zendy; Sabine Rauscher | Zendy; Sebastian Burgstaller-Muehlbacher | Zendy; Ingrid Faé | Zendy; Gottfried Fischer | Zendy; Hubert Pehamberger | Zendy; Ichiro Okamoto | Zendy

Open Access

Human Determinants and the Role of Melanocortin-1 Receptor Variants in Melanoma Risk Independent of UV Radiation Exposure

Author(s) -

Judith Wendt,

Sabine Rauscher,

Sebastian Burgstaller-Muehlbacher,

Ingrid Faé,

Gottfried Fischer,

Hubert Pehamberger,

Ichiro Okamoto

Publication year - 2016

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2016.0050

Subject(s) - medicine , melanoma , melanocortin 1 receptor , skin cancer , dermatology , melanocyte , oncology , cancer , genetics , cancer research , gene , phenotype , biology

Despite the unquestioned relationship of UV radiation (UVR) exposure and melanoma development, UVR-independent development of melanoma has only recently been described in mice. These findings in mice highlight the importance of the genetic background of the host and could be relevant for preventive measures in humans.

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