Association of Rosacea With Risk for Glioma in a Danish Nationwide Cohort Study
Author(s) -
Alexander Egeberg,
Peter Riis Hansen,
Gunnar Gislason,
Jacob P. Thyssen
Publication year - 2016
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2015.5549
Subject(s) - medicine , rosacea , incidence (geometry) , population , glioma , poisson regression , cohort , danish , cohort study , rate ratio , pediatrics , demography , dermatology , environmental health , linguistics , philosophy , physics , cancer research , sociology , optics , acne
Rosacea, a common facial skin disorder, has a poorly understood pathogenesis in which increased matrix metalloproteinase activity might play an important role. Glioma accounts for 80% of all primary malignant tumors in the central nervous system, and these tumors also show upregulation of certain matrix metalloproteinases.
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