Association of Sirolimus Use With Risk for Skin Cancer in a Mixed-Organ Cohort of Solid-Organ Transplant Recipients With a History of Cancer
Author(s) -
Pritesh S. Karia,
Jamil Azzi,
Eliot Heher,
Victoria M. Hills,
Chrysalyne D. Schmults
Publication year - 2016
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2015.5548
Subject(s) - medicine , sirolimus , organ transplantation , cancer , skin cancer , cohort , solid organ , oncology , transplantation
Solid-organ transplant recipients (OTRs) are at an increased risk for skin cancer. Prior studies have demonstrated a reduced incidence of skin cancer in renal OTRs treated with sirolimus. However, little information exists on the use of sirolimus for the prevention of skin cancer in nonrenal OTRs or those already diagnosed as having a posttransplant cancer.
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