The Expression Status and Prognostic Value of Cancer Stem Cell Biomarker CD133 in Cutaneous Squamous Cell Carcinoma
Author(s) -
Rui Xu,
Mu-Yan Cai,
Rong-Zhen Luo,
Xin Tian,
Jian-de Han,
Mu-Kai Chen
Publication year - 2015
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2015.3781
Subject(s) - tissue microarray , medicine , biomarker , immunohistochemistry , cancer , cancer stem cell , pathology , oncology , receiver operating characteristic , proportional hazards model , survival analysis , stem cell marker , cancer research , stem cell , biology , biochemistry , genetics
The CD133 protein has been considered a key biomarker of cancer stem cells in various cancers. However, the expression status and prognostic significance of CD133 in cutaneous squamous cell carcinoma (cSCC) are poorly understood.
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