Narrowband UV-B Phototherapy for Steroid-Refractory Sclerotic Chronic Cutaneous Graft-vs-Host Disease | Zendy

Eric J. Sorenson | Zendy; Rachel McAndrew | Zendy; Viraat Patel | Zendy; Aaron C. Logan | Zendy; John Koo | Zendy; Ethan Levin | Zendy

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Narrowband UV-B Phototherapy for Steroid-Refractory Sclerotic Chronic Cutaneous Graft-vs-Host Disease

Author(s) -

Eric J. Sorenson,

Rachel McAndrew,

Viraat Patel,

Aaron C. Logan,

John Koo,

Ethan Levin

Publication year - 2015

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2015.0175

Subject(s) - medicine , graft versus host disease , prednisone , extracorporeal photopheresis , dermatology , chronic myelogenous leukemia , mycosis fungoides , refractory (planetary science) , tacrolimus , photopheresis , disease , leukemia , surgery , transplantation , pathology , lymphoma , physics , astrobiology

Chronic graft-vs-host disease (GVHD) affects 50% to 70% of patients who receive allogeneic hematopoietic cell transplants (HCTs), and the skin is the most common site of involvement. Chronic cutaneous GVHD can present with sclerotic or nonsclerotic changes of the skin and often requires treatment with systemic immunosuppressants, extracorporeal photopheresis, or phototherapy. We describe the first reported case, to our knowledge, of the effective treatment of sclerotic chronic cutaneous GVHD with narrowband UV-B (NB UV-B) phototherapy.

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