Moon Jellyfish Stings
Author(s) -
Brian J. Simmons,
Robert Griffith,
Leyre FaltoAizpurua,
Keyvan Nouri
Publication year - 2014
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2014.4644
Subject(s) - medicine , jellyfish , scyphozoa , envenomation , dermatology , venom , fishery , cnidaria , coral , biology , art , visual arts
formed. The exanthema and the eosinophilia decreased gradually until normalization was achieved on day 16. On day 19, vemurafenib therapy was discontinued, and within 7 days thereafter, the fever had improved, and the electrolyte profile had normalized. Tumor assessment showed a major tumoral response. On day 29, vemurafenib treatment was restarted at half dose, leading within 21 days (day 50) to a relapse of hypokalemia and hypouricemia with acute urinary loss but without relapse of fever, exanthema, or eosinophilia. Vemurafenib treatment was then definitively stopped, followed by normalization of electrolytic findings within 5 days. At that time, treatment with dabrafenib, another BRAF inhibitor, was started. At last follow-up 5 months later, no adverse event had occurred.
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