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Fanconi Syndrome Induced by Vemurafenib
Author(s) -
Daphné Denis,
Nathalie Franck,
F. Fichel,
C. Lévi,
N. Dupin
Publication year - 2014
Publication title -
jama dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.128
H-Index - 166
eISSN - 2168-6084
pISSN - 2168-6068
DOI - 10.1001/jamadermatol.2014.4529
Subject(s) - medicine , vemurafenib , dermatology , cancer research , melanoma , metastatic melanoma
lyzing group A streptococci, notably without prior drug intake. Again, intraoral pustules were observed. During this episode, clinical and histologic findings were consistent with GPP.1 The patient recalled a similar episode 20 years before with a generalized pustular eruption with systemic symptoms without prior drug intake. The patient was given oral clarithromycin (500 mg twice daily) for his throat infection and 2 infusions with infliximab (5 mg/kg of body weight), which resulted in rapid clearance of the lesions.

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