Sarcoidosis and Psoriasis | Zendy

Karolyn A. Wanat | Zendy; András Schaffer | Zendy; Veronica Richardson | Zendy; Abby VanVoorhees | Zendy; Misha Rosenbach | Zendy

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Sarcoidosis and Psoriasis

Author(s) -

Karolyn A. Wanat,

András Schaffer,

Veronica Richardson,

Abby VanVoorhees,

Misha Rosenbach

Publication year - 2013

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2013.4256

Subject(s) - sarcoidosis , psoriasis , medicine , cutaneous sarcoidosis , pathogenesis , dermatology , granulomatous disease , systemic disease , disease , immunology , granuloma , pathology

Sarcoidosis is a chronic multisystem disorder characterized by the formation of noncaseating epithelioid cell granulomas affecting multiple organ systems. The role of the type 1 helper T (T(H)1) cell in sarcoidal granuloma formation has been well documented, and the T(H)17 pathway in sarcoidosis is just now being investigated. T(H)17 cells are also known to involved in the pathogenesis of psoriasis, and the coexistence of sarcoidosis and psoriasis is mechanistically plausible based on potential shared underlying immunologic pathways.

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