Saliva Polymerase Chain Reaction Assay for Detection and Follow-up of Herpesvirus Reactivation in Patients With Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) | Zendy

V. Descamps | Zendy; M. Avenel-Audran | Zendy; L. ValeyrieAllanore | Zendy; Benoît Bensaïd | Zendy; A. Barbaud | Zendy; Mustafa Al Jawhari | Zendy; Sylvie RangerRogez | Zendy

Open Access

Saliva Polymerase Chain Reaction Assay for Detection and Follow-up of Herpesvirus Reactivation in Patients With Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS)

Author(s) -

V. Descamps,

M. Avenel-Audran,

L. ValeyrieAllanore,

Benoît Bensaïd,

A. Barbaud,

Mustafa Al Jawhari,

Sylvie RangerRogez

Publication year - 2013

Publication title -

jama dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.128

H-Index - 166

eISSN - 2168-6084

pISSN - 2168-6068

DOI - 10.1001/jamadermatol.2013.2018

Subject(s) - saliva , medicine , polymerase chain reaction , real time polymerase chain reaction , immunology , herpesviridae , viral shedding , virology , gammaherpesvirinae , virus , cytomegalovirus , epstein–barr virus , varicella zoster virus , human herpesvirus 6 , viral disease , biology , gene , biochemistry

Reactivations of human herpesviruses (HHVs) contribute to the development of drug reaction with eosinophilia and systemic symptoms (DRESS). Diagnosis of HHV reactivation is conventionally based on quantitative real-time polymerase chain reaction (PCR) analysis of blood samples, but these viruses are present in the oropharynx and are shed in saliva.

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