Open AccessAssociation of Elevated Plasma Endothelin-1 Levels With Pulmonary Hypertension, Mortality, and Heart Failure in African American Individuals
Author(s) -
Matthew Jankowich,
WenChih Wu,
Gaurav Choudhary
Publication year - 2016
Publication title -
jama cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.108
H-Index - 63
eISSN - 2380-6591
pISSN - 2380-6583
DOI - 10.1001/jamacardio.2016.0962
Subject(s) - medicine , pulmonary hypertension , endothelin 1 , heart failure , cardiology , endothelin receptor , plasma levels , african american , ethnology , receptor , history
Despite pathophysiological links between endothelin-1 and pulmonary vascular remodeling, to our knowledge, the association between plasma endothelin-1 levels and pulmonary hypertension has not been studied in the general population. Also, whether endothelin-1 can predict future heart failure and mortality, outcomes that are associated with pulmonary hypertension, in a population cohort is unclear.
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