Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus | Zendy

Darren K. McGuire | Zendy; Frans Van de Werf | Zendy; Paul W. Armstrong | Zendy; Eberhard Standl | Zendy; Joerg Koglin | Zendy; Jennifer B. Green | Zendy; M. Angelyn Bethel | Zendy; Jan H. Cornel | Zendy; Renato D. Lópes | Zendy; Sigrun Halvorsen | Zendy; Giuseppe Ambrosio | Zendy; John B. Buse | Zendy; Robert G. Josse | Zendy; John M. Lachin | Zendy; Michael Pencina | Zendy; Jyotsna Garg | Zendy; Yuliya Lokhnygina | Zendy; Rury R. Holman | Zendy; Eric D. Peterson | Zendy

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Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus

Author(s) -

Darren K. McGuire,

Frans Van de Werf,

Paul W. Armstrong,

Eberhard Standl,

Joerg Koglin,

Jennifer B. Green,

M. Angelyn Bethel,

Jan H. Cornel,

Renato D. Lópes,

Sigrun Halvorsen,

Giuseppe Ambrosio,

John B. Buse,

Robert G. Josse,

John M. Lachin,

Michael Pencina,

Jyotsna Garg,

Yuliya Lokhnygina,

Rury R. Holman,

Eric D. Peterson

Publication year - 2016

Publication title -

jama cardiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.108

H-Index - 63

eISSN - 2380-6591

pISSN - 2380-6583

DOI - 10.1001/jamacardio.2016.0103

Subject(s) - sitagliptin , medicine , placebo , sitagliptin phosphate , type 2 diabetes mellitus , dipeptidyl peptidase 4 inhibitor , heart failure , type 2 diabetes , randomized controlled trial , diabetes mellitus , endocrinology , pathology , alternative medicine

Previous trial results have suggested that dipeptidyl peptidase 4 inhibitor (DPP4i) use might increase heart failure (HF) risk in type 2 diabetes mellitus (T2DM). The DPP4i sitagliptin has been shown to be noninferior to placebo with regard to primary and secondary composite atherosclerotic cardiovascular (CV) outcomes in the Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS).

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