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Clinical Applications of Blood-Derived and Marrow-Derived Stem Cells for Nonmalignant Diseases
Author(s) -
Richard K. Burt,
Yvonne Loh,
William Pearce,
Nirat Beohar,
Walter G. Barr,
Robert L. Craig,
Yanting Wen,
Jonathan A. Rapp,
John A. Kessler
Publication year - 2008
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.299.8.925
Subject(s) - medicine , stem cell , bone marrow , clinical trial , umbilical cord , haematopoiesis , confusion , oncology , immunology , genetics , biology , psychology , psychoanalysis
Stem cell therapy is rapidly developing and has generated excitement and promise as well as confusion and at times contradictory results in the lay and scientific literature. Many types of stem cells show great promise, but clinical application has lagged due to ethical concerns or difficulties in harvesting or safely and efficiently expanding sufficient quantities. In contrast, clinical indications for blood-derived (from peripheral or umbilical cord blood) and bone marrow-derived stem cells, which can be easily and safely harvested, are rapidly increasing.

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