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Costs and Effectiveness of Ximelagatran for Stroke Prophylaxis in Chronic Atrial Fibrillation
Author(s) -
Cara O’Brien
Publication year - 2005
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.293.6.699
Subject(s) - medicine , ximelagatran , warfarin , atrial fibrillation , stroke (engine) , aspirin , quality adjusted life year , direct thrombin inhibitor , cost effectiveness , cardiology , dabigatran , mechanical engineering , risk analysis (engineering) , engineering
Recent trials have found that ximelagatran and warfarin are equally effective in stroke prevention for patients with atrial fibrillation. Because ximelagatran can be taken in a fixed, oral dose without international normalized ratio monitoring and may have a lower risk of hemorrhage, it might improve quality-adjusted survival compared with dose-adjusted warfarin.

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