Open AccessExposure to Infant Siblings During Early Life and Risk of Multiple Sclerosis
Author(s) -
Anne–Louise Ponsonby
Publication year - 2005
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.293.4.463
Subject(s) - medicine , odds ratio , confidence interval , pediatrics , multiple sclerosis , hygiene hypothesis , population , case control study , mononucleosis , breastfeeding , sibling , immunology , immune system , virus , environmental health , psychology , developmental psychology
The "hygiene hypothesis" has implicated sibship as a marker of infection load during early life and suggests that exposure or reexposure to infections can influence the developing immune system. Viral infection has also been implicated in the pathogenesis of multiple sclerosis (MS).
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