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Electrocardiographic and Hemodynamic Effects of a Multicomponent Dietary Supplement Containing Ephedra and Caffeine
Author(s) -
Brian F. McBride,
Angeliki K. Karapanos,
Agnes Krudysz,
Jeffrey Kluger,
Craig I Coleman,
C Michael White
Publication year - 2004
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.291.2.216
Subject(s) - medicine , placebo , qt interval , crossover study , caffeine , confidence interval , blood pressure , adverse effect , anesthesia , cardiology , alternative medicine , pathology
Metabolife 356, a multicomponent dietary supplement containing ephedra and caffeine (DSEC) in addition to several other components, is the top-selling dietary weight loss supplement. Given its common use, anecdotal reports of cardiovascular and cerebrovascular adverse events, and paucity of safety data, further research with this DSEC was warranted.

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