Intrathecal Ziconotide in the Treatment of Refractory Pain in Patients With Cancer or AIDS
Author(s) -
Peter S. Staats,
Thomas Yearwood,
Steven G. Charapata,
R. Presley,
Mark S. Wallace,
Michael G. ByasSmith,
Robert B. Fisher,
David A. Bryce,
Eugene A. Mangieri,
Robert R. Luther,
Martha Mayo,
Dawn McGuire,
David Ellis
Publication year - 2004
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.291.1.63
Subject(s) - medicine , placebo , anesthesia , morphine , refractory (planetary science) , opioid , cancer pain , visual analogue scale , adverse effect , population , cancer , physics , alternative medicine , receptor , environmental health , pathology , astrobiology
Ziconotide (formerly SNX-111) selectively blocks N-type voltage-sensitive calcium channels and may be effective in patients with pain that is refractory to opioid therapy or those with intolerable opioid-related adverse effects.
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