Sertraline Treatment of Major Depression in Patients With Acute MI or Unstable Angina | Zendy

Alexander H. Glassman | Zendy

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Sertraline Treatment of Major Depression in Patients With Acute MI or Unstable Angina

Author(s) -

Alexander H. Glassman

Publication year - 2002

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.288.6.701

Subject(s) - medicine , sertraline , unstable angina , major depressive disorder , ejection fraction , placebo , myocardial infarction , depression (economics) , angina , randomized controlled trial , adverse effect , clinical global impression , cardiology , heart failure , antidepressant , alternative medicine , macroeconomics , pathology , amygdala , hippocampus , economics

Major depressive disorder (MDD) occurs in 15% to 23% of patients with acute coronary syndromes and constitutes an independent risk factor for morbidity and mortality. However, no published evidence exists that antidepressant drugs are safe or efficacious in patients with unstable ischemic heart disease.

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