Immunologic and Virologic Effects of Subcutaneous Interleukin 2 in Combination With Antiretroviral Therapy | Zendy

Richard T. Davey | Zendy; Robert L. Murphy | Zendy; Francesco Graziano | Zendy; Steven Boswell | Zendy; Andrew T. Pavia | Zendy; Manuel Cancio | Zendy; Jeffrey P. Nadler | Zendy; Doreen Chaitt | Zendy; Robin Dewar | Zendy; David Sahner | Zendy; A M Duliege | Zendy; William B. Capra | Zendy; Wai Yie Leong | Zendy; Martin Giedlin | Zendy; H. Clifford Lane | Zendy; James O. Kahn | Zendy

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Immunologic and Virologic Effects of Subcutaneous Interleukin 2 in Combination With Antiretroviral Therapy

Author(s) -

Richard T. Davey,

Robert L. Murphy,

Francesco Graziano,

Steven Boswell,

Andrew T. Pavia,

Manuel Cancio,

Jeffrey P. Nadler,

Doreen Chaitt,

Robin Dewar,

David Sahner,

A M Duliege,

William B. Capra,

Wai Yie Leong,

Martin Giedlin,

H. Clifford Lane,

James O. Kahn

Publication year - 2000

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.284.2.183

Subject(s) - medicine , antiretroviral therapy , combination therapy , aldesleukin , immunology , randomized controlled trial , lymphocyte , interleukin 2 , gastroenterology , interleukin , viral load , human immunodeficiency virus (hiv) , cytokine

While interleukin 2 (IL-2) is capable of inducing a marked expansion of the CD4 T-lymphocyte pool, limited data exist on whether IL-2 treatment can add significantly to the immunologic and virologic effects of potent antiretroviral therapy (ART).

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