Interpreting Diagnostic Tests for SARS-CoV-2 | Zendy

Nandini Sethuraman | Zendy; Sundararaj Stanleyraj Jeremiah | Zendy; Akihide Ryo | Zendy

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Interpreting Diagnostic Tests for SARS-CoV-2

Author(s) -

Nandini Sethuraman,

Sundararaj Stanleyraj Jeremiah,

Akihide Ryo

Publication year - 2020

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2020.8259

Subject(s) - medicine , covid-19 , betacoronavirus , virology , coronavirus infections , pandemic , pathology , outbreak , infectious disease (medical specialty) , disease

The pandemic of coronavirus disease 2019 (COVID-19) continues to affect much of the world. Knowledge of diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still evolving, and a clear understanding of the nature of the tests and interpretation of their findings is important. This Viewpoint describes how to interpret 2 types of diagnostic tests commonly in use for SARS-CoV-2 infections—reverse transcriptase–polymerase chain reaction (RT-PCR) and IgM and IgG enzyme-linked immunosorbent assay (ELISA)—and how the results may vary over time (Figure).

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