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Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients With Acute Ischemic Stroke
Author(s) -
Shumei Man,
Ying Xian,
DaJuanicia N. Holmes,
Roland Matsouaka,
Jeffrey L. Saver,
Eric E. Smith,
Deepak L. Bhatt,
Lee H. Schwamm,
Gregg C. Fonarow
Publication year - 2020
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2020.5697
Subject(s) - medicine , interquartile range , stroke (engine) , retrospective cohort study , thrombolysis , emergency medicine , ischemic stroke , tissue plasminogen activator , cohort , acute stroke , ischemia , myocardial infarction , mechanical engineering , engineering
Earlier administration of intravenous tissue plasminogen activator (tPA) in acute ischemic stroke is associated with reduced mortality by the time of hospital discharge and better functional outcomes at 3 months. However, it remains unclear whether shorter door-to-needle times translate into better long-term outcomes.

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