Open AccessScreening for Hepatitis B Virus Infection in Adolescents and Adults
Author(s) -
Alex H. Krist,
Karina W. Davidson,
Carol M. Mangione,
Michael J. Barry,
Michael D. Cabana,
Aaron B. Caughey,
Katrina E Donahue,
Chyke A. Doubeni,
John W. Epling,
Martha Kubik,
Gbenga Ogedegbe,
Douglas K Owens,
Lori Pbert,
Michael J. Silverstein,
Melissa A. Simon,
ChienWen Tseng,
John B. Wong
Publication year - 2020
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2020.22980
Subject(s) - medicine , asymptomatic , population , hepatitis b virus , transmission (telecommunications) , cohort , hepatitis b , chronic infection , pediatrics , immunology , environmental health , virus , immune system , electrical engineering , engineering
An estimated 862 000 persons in the US are living with chronic infection with hepatitis B virus (HBV). Persons born in regions with a prevalence of HBV infection of 2% or greater, such as countries in Africa and Asia, the Pacific Islands, and parts of South America, often become infected at birth and account for up to 95% of newly reported chronic infections in the US. Other high-prevalence populations include persons who inject drugs; men who have sex with men; persons with HIV infection; and sex partners, needle-sharing contacts, and household contacts of persons with chronic HBV infection. Up to 60% of HBV-infected persons are unaware of their infection, and many remain asymptomatic until onset of cirrhosis or end-stage liver disease.
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