Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer | Zendy

James Yarmolinsky | Zendy; Caroline J. Bull | Zendy; Emma E. Vincent | Zendy; Jamie Robinson | Zendy; Axel Walther | Zendy; George Davey Smith | Zendy; Sarah J. Lewis | Zendy; Caroline L. Relton | Zendy; Richard M. Martin | Zendy

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Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer

Author(s) -

James Yarmolinsky,

Caroline J. Bull,

Emma E. Vincent,

Jamie Robinson,

Axel Walther,

George Davey Smith,

Sarah J. Lewis,

Caroline L. Relton,

Richard M. Martin

Publication year - 2020

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2020.0150

Subject(s) - medicine , mendelian randomization , single nucleotide polymorphism , pcsk9 , genome wide association study , ovarian cancer , oncology , statin , population , genetics , bioinformatics , cancer , cholesterol , biology , genotype , lipoprotein , gene , ldl receptor , environmental health , genetic variants

Preclinical and epidemiological studies indicate a potential chemopreventive role of statins in epithelial ovarian cancer risk.

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