Association Between Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Stenosis and Mortality or Stroke | Zendy

Raj Makkar | Zendy; SungHan Yoon | Zendy; Martin B. Leon | Zendy; Tarun Chakravarty | Zendy; Michael Rinaldi | Zendy; Pinak Shah | Zendy; Eric Skipper | Zendy; Vinod H. Thourani | Zendy; Vasilis Babaliaros | Zendy; Wen Cheng | Zendy; Alfredo Trento | Zendy; Sreekanth Vemulapalli | Zendy; Samir Kapadia | Zendy; Susheel Kodali | Zendy; Michael J. Mack | Zendy; Gilbert H.L. Tang | Zendy; Tsuyoshi Kaneko | Zendy

Open Access

Association Between Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Stenosis and Mortality or Stroke

Author(s) -

Raj Makkar,

SungHan Yoon,

Martin B. Leon,

Tarun Chakravarty,

Michael Rinaldi,

Pinak Shah,

Eric Skipper,

Vinod H. Thourani,

Vasilis Babaliaros,

Wen Cheng,

Alfredo Trento,

Sreekanth Vemulapalli,

Samir Kapadia,

Susheel Kodali,

Michael J. Mack,

Gilbert H.L. Tang,

Tsuyoshi Kaneko

Publication year - 2019

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2019.7108

Subject(s) - medicine , cardiology , stenosis , bicuspid aortic valve , stroke (engine) , valve replacement , aortic valve replacement , aortic valve stenosis , bicuspid valve , aortic valve , mechanical engineering , engineering

In this preliminary, registry-based study of propensity-matched patients who had undergone transcatheter aortic valve replacement for aortic stenosis, patients with bicuspid vs tricuspid aortic stenosis had no significant difference in 30-day or 1-year mortality but had increased 30-day risk for stroke. Because of the potential for selection bias and the absence of a control group treated surgically for bicuspid stenosis, randomized trials are needed to adequately assess the efficacy and safety of transcatheter aortic valve replacement for bicuspid aortic stenosis.

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