Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients | Zendy

Murali K. Matta | Zendy; Robbert Zusterzeel | Zendy; Nageswara Rao Pilli | Zendy; Vikram Patel | Zendy; Donna A. Volpe | Zendy; Jeffry Florian | Zendy; Luke S. Oh | Zendy; Edward D. Bashaw | Zendy; Issam Zineh | Zendy; Carlos Sanabria | Zendy; S. Kemp | Zendy; Anthony Godfrey | Zendy; Steven A. Adah | Zendy; Sergio G. Coelho | Zendy; Jian Wang | Zendy; Lesley-Anne Furlong | Zendy; Charles J. Ganley | Zendy; Theresa M. Michele | Zendy; David G. Strauss | Zendy

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Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients

Author(s) -

Murali K. Matta,

Robbert Zusterzeel,

Nageswara Rao Pilli,

Vikram Patel,

Donna A. Volpe,

Jeffry Florian,

Luke S. Oh,

Edward D. Bashaw,

Issam Zineh,

Carlos Sanabria,

S. Kemp,

Anthony Godfrey,

Steven A. Adah,

Sergio G. Coelho,

Jian Wang,

Lesley-Anne Furlong,

Charles J. Ganley,

Theresa M. Michele,

David G. Strauss

Publication year - 2019

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2019.5586

Subject(s) - medicine , lotion , coefficient of variation , active ingredient , randomized controlled trial , plasma concentration , pharmacology , chromatography , chemistry

The US Food and Drug Administration (FDA) has provided guidance that sunscreen active ingredients with systemic absorption greater than 0.5 ng/mL or with safety concerns should undergo nonclinical toxicology assessment including systemic carcinogenicity and additional developmental and reproductive studies.

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