Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer | Zendy

Kimmie Ng | Zendy; Halla Nimeiri | Zendy; Nadine J. McCleary | Zendy; Thomas A. Abrams | Zendy; Matthew B. Yurgelun | Zendy; James M. Cleary | Zendy; Douglas A. Rubinson | Zendy; Deborah Schrag | Zendy; Rebecca A. Miksad | Zendy; Andrea J. Bullock | Zendy; Jill N. Allen | Zendy; Dan Sayam Zuckerman | Zendy; Emily Chan | Zendy; Jennifer A. Chan | Zendy; Brian M. Wolpin | Zendy; Michael Constantine | Zendy; Douglas Weckstein | Zendy; Meredith A. Faggen | Zendy; Christian A. Thomas | Zendy; Chryssanthi Kournioti | Zendy; Chen Yuan | Zendy; Christine Ganser | Zendy; Brittney Wilkinson | Zendy; Christopher Mackintosh | Zendy; Hui Zheng | Zendy; Bruce W. Hollis | Zendy; Jeffrey A. Meyerhardt | Zendy; Charles S. Fuchs | Zendy

Open Access

Effect of High-Dose vs Standard-Dose Vitamin D₃ Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer

Author(s) -

Kimmie Ng,

Halla Nimeiri,

Nadine J. McCleary,

Thomas A. Abrams,

Matthew B. Yurgelun,

James M. Cleary,

Douglas A. Rubinson,

Deborah Schrag,

Rebecca A. Miksad,

Andrea J. Bullock,

Jill N. Allen,

Dan Sayam Zuckerman,

Emily Chan,

Jennifer A. Chan,

Brian M. Wolpin,

Michael Constantine,

Douglas Weckstein,

Meredith A. Faggen,

Christian A. Thomas,

Chryssanthi Kournioti,

Chen Yuan,

Christine Ganser,

Brittney Wilkinson,

Christopher Mackintosh,

Hui Zheng,

Bruce W. Hollis,

Jeffrey A. Meyerhardt,

Charles S. Fuchs

Publication year - 2019

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2019.2402

Subject(s) - medicine , hazard ratio , colorectal cancer , bevacizumab , clinical endpoint , vitamin d and neurology , progression free survival , gastroenterology , proportional hazards model , chemotherapy , vitamin , cancer , vitamin d deficiency , oncology , randomized controlled trial , surgery , confidence interval

In observational studies, higher plasma 25-hydroxyvitamin D (25[OH]D) levels have been associated with improved survival in metastatic colorectal cancer (CRC).

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