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Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation
Author(s) -
Paul J. Young,
Sean M. Bagshaw,
Andrew Forbes,
Alistair Nichol,
Stephen E. Wright,
Michael Bailey,
Rinaldo Bellomo,
Richard Beasley,
Kathy Brickell,
Glenn M. Eastwood,
David Gattas,
Frank van Haren,
Edward Litton,
Diane Mackle,
Colin McArthur,
Shay McGuinness,
Paul Mouncey,
Leanlove Navarra,
Dawn Opgenorth,
David Pilcher,
Manoj Saxena,
Steve Webb,
Daisy Wiley,
Kathy Rowan
Publication year - 2020
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2019.22190
Subject(s) - medicine , stress ulcer , mechanical ventilation , anesthesia , histamine , intensive care medicine
Proton pump inhibitors (PPIs) or histamine-2 receptor blockers (H2RBs) are often prescribed for patients as stress ulcer prophylaxis drugs in the intensive care unit (ICU). The comparative effect of these drugs on mortality is unknown.

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