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Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock
Author(s) -
Glenn Hernández,
Gustavo A. OspinaTascón,
Lucas Petri Damiani,
Elisa Estenssoro,
Arnaldo Dubín,
Javier Hurtado,
Gilberto Friedman,
Ricardo Castro,
Leyla Alegría,
Jean–Louis Teboul,
Maurizio Cecconi,
Giorgio Ferri,
Manuel Jibaja,
Ronald Pairumani,
Paula Virginia Fernández,
D. Barahona,
Vladimir Granda-Luna,
Alexandre Biasi Cavalcanti,
Jan Bakker
Publication year - 2019
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2019.0071
Subject(s) - medicine , resuscitation , septic shock , sofa score , randomization , organ dysfunction , hazard ratio , perfusion , intensive care unit , shock (circulatory) , randomized controlled trial , intensive care , renal replacement therapy , mechanical ventilation , sepsis , anesthesia , intensive care medicine , confidence interval
Abnormal peripheral perfusion after septic shock resuscitation has been associated with organ dysfunction and mortality. The potential role of the clinical assessment of peripheral perfusion as a target during resuscitation in early septic shock has not been established.

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