Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock
Author(s) -
William F. McIntyre,
Kevin J. Um,
Waleed Alhazzani,
A. Lengyel,
Ludhmila Abrahão Hajjar,
Anthony Gordon,
François Lamontagne,
Jeff S. Healey,
Richard Whitlock,
Emilie P. BelleyCôté
Publication year - 2018
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2018.4528
Subject(s) - medicine , vasopressin , atrial fibrillation , randomized controlled trial , cardiology , shock (circulatory) , anesthesia , adverse effect
Vasopressin is an alternative to catecholamine vasopressors for patients with distributive shock-a condition due to excessive vasodilation, most frequently from severe infection. Blood pressure support with a noncatecholamine vasopressor may reduce stimulation of adrenergic receptors and decrease myocardial oxygen demand. Atrial fibrillation is common with catecholamines and is associated with adverse events, including mortality and increased length of stay (LOS).
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