Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants | Zendy

Souvik Mitra | Zendy; Iván D. Flórez | Zendy; María Tamayo | Zendy; Lawrence Mbuagbaw | Zendy; Thuva Vanniyasingam | Zendy; Areti Angeliki Veroniki | Zendy; Adriana M. Zea | Zendy; Yuan Zhang | Zendy; Behnam Sadeghirad | Zendy; Lehana Thabane | Zendy

Open Access

Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants

Author(s) -

Souvik Mitra,

Iván D. Flórez,

María Tamayo,

Lawrence Mbuagbaw,

Thuva Vanniyasingam,

Areti Angeliki Veroniki,

Adriana M. Zea,

Yuan Zhang,

Behnam Sadeghirad,

Lehana Thabane

Publication year - 2018

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2018.1896

Subject(s) - medicine , odds ratio , ductus arteriosus , ibuprofen , intraventricular hemorrhage , placebo , acetaminophen , gestational age , randomized controlled trial , necrotizing enterocolitis , anesthesia , adverse effect , number needed to treat , confidence interval , pediatrics , relative risk , pregnancy , alternative medicine , pathology , biology , pharmacology , genetics

Despite increasing emphasis on conservative management of patent ductus arteriosus (PDA) in preterm infants, different pharmacotherapeutic interventions are used to treat those developing a hemodynamically significant PDA.

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